Overview
Peripheral nerve stimulation (PNS) delivers targeted electrical stimulation directly to a peripheral nerve — outside the spinal canal — to modulate pain signals at their source. Unlike spinal cord stimulation, which targets the central nervous system, PNS targets the peripheral nervous system: the specific nerve responsible for a patient's focal pain. This makes PNS particularly valuable for pain confined to a specific nerve distribution — such as post-surgical nerve injuries, limb pain, occipital neuralgia, or shoulder pain. Dr. Migdale is certified in the SPRINT PNS System (May 2025) and has specific clinical and research experience in intercostal PNS for post-mastectomy and post-thoracotomy pain.
How Peripheral Nerve Stimulation Works
PNS leads are placed percutaneously (through the skin with a needle, without open surgery) near the target peripheral nerve using ultrasound or fluoroscopic guidance. The lead delivers low-level electrical pulses that modulate pain signaling in the nerve — reducing abnormal pain transmission without blocking normal function. Modern PNS systems can provide meaningful relief with minimal stimulation, and many patients report that stimulation 'quiets' their pain rather than masking it.
The SPRINT PNS System
The SPRINT Peripheral Nerve Stimulation System (SPR Therapeutics) is an FDA-cleared PNS device designed for temporary percutaneous use — typically 60 days. Unlike permanent PNS implants, SPRINT uses a percutaneous lead that is placed and removed without surgery, making it both a therapeutic and a diagnostic tool. Evidence supports SPRINT for shoulder pain, low back pain, and various peripheral nerve pain conditions. Dr. Migdale completed SPRINT PNS education certification in May 2025.
Applications
PNS is used for: post-surgical neuropathic pain (intercostal, post-mastectomy, post-thoracotomy); occipital neuralgia and refractory headache; shoulder pain; knee pain; ankle and foot pain; phantom limb pain; and peripheral nerve injuries. The ability to target any accessible peripheral nerve makes PNS one of the most versatile tools in the neuromodulation toolkit.